INDICATORS ON IL-2 THERAPY FOR MELANOMA YOU SHOULD KNOW

It is nicely recognized that IL-two can be a pleiotropic cytokine positioned at the crossroads of T cell activation and regulation. As such, it really is essential to engineer an IL-2 molecule which is biased to effector cells bearing the intermediate affinity receptor, for instance naïve and memory CD8+ T cells and NK cells, compared to Treg cell